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60nt RNA 2’Ome Modified Synthesis Report (Using 1000A Co-Polymer Coated CPG with Unylinker)

1. Introduction This experiment was designed to evaluate the performance of our 1000 Å Co-Polymer Coated CPG in the practical synthesis of medium-length oligonucleotides, with a specific focus on RNA synthesis. Notably, this evaluation was conducted under our high-loading condition of 105 µmol/g, whereas traditional modified CPG of the same pore size typically exhibits a […]

Synthesis Report for 120 nt TBDMS RNA Synthesis by using 2000A co-polymer coated CPG with unylinker

Introduction 120 nt RNA is considered a long-chain RNA product, and the development of RNA therapeutics is driving increasing demand for longer and more highly modified RNA sequences. Long-chain RNA synthesis becomes increasingly challenging when bulky protecting groups such as TBDMS are introduced. The steric demand of TBDMS chemistry can negatively affect coupling efficiency and

COA for Co-Polymer Coated CPG 2000Å+ 2′-OMe-rU

Certificate of Analysis (COA) Product Information Item Details Product Name Co-Polymer Coated CPG 2000Å+ 2′-OMe-rU Lot# 86025-02036A Mfg Date 5/19/2026 Report Date 5/20/2026 Quality Control Results Items Specification QC Data Results Pore Size 2000Å ± 200 2015Å Pass Particle Size 120–180 Mesh 120–180 Mesh Pass Bulk Density 0.22–0.3 g/cm³ 0.25 g/cm³ Pass Surface Area 25–40

Co-Polymer Coated CPG 1000Å+ 2′-OMe-rU

Certificate of Analysis (COA) Product Information Item Details Product Name Co-Polymer Coated CPG 1000Å+ 2′-OMe-rU Lot# 86025-02030A Mfg Date 4/1/2026 Report Date 4/3/2026 Quality Control Results Items Specification QC Data Results Pore Size 1000Å ± 200 1015Å Pass Particle Size 120–180 Mesh 120–180 Mesh Pass Bulk Density 0.22–0.3 g/cm³ 0.23 g/cm³ Pass Surface Area 25–40

Co-Polymer Coated CPG 2000Å+ UnyLinker-Ph COA Report

Certificate of Analysis (COA) Product Identification Technical Specifications & Quality Control Results Test Items Specification Standard QC Testing Data Test Results Pore Size 2000Å ± 200 2015 Å Pass Particle Size 120-180 Mesh 120-180 Mesh Pass Bulk Density 0.22 – 0.3 g/cm³ 0.25 g/cm³ Pass Surface Area 25 – 40 m²/g 33.19 m²/g Pass Nucleoside

Co-Polymer Coated CPG 1000Å+ UnyLinker-Ph COA Report

Certificate of Analysis Product Information Specifications and Results Items Specification QC Data Results Pore Size 1000ű200 1015 Å Pass Particle Size 120-180 Mesh 120-180 Mesh Pass Bulk Density 0.22-0.3g/cm³ 0.23g/cm³ Pass Surface Area 25-40m²/g 33.19m²/g Pass Nucleoside Loading > 80µmol/g 92 µmol/g Pass Appearance Off-white solid Off-white solid Pass Technical Summary This Certificate of Analysis

2000A Hyper-Link CPG for 81nt Oligonucleotide Synthesis Test Report

Introduction This report presents a comprehensive performance evaluation and comparative analysis across four distinct CPG solid support samples used for oligonucleotide synthesis. Through the data provided in this report, a clear performance gap is observed between conventional CPG and Poresyn’s new polystyrene+CPG architecture. Synthesis Test Report – Poresyn Solutions Synthesis Performance Analysis Poresyn Solutions |

Co-Polymer Coated CPG 2000A Unylinker(N-PH) Synthesis Test Result

Oligonucleotide Synthesis Test Results: Batch 20260206 Test Information: Synthesis Results: Scale A260 OD nmol Yield (%) Purity (%) Mass (%) 1 µmol 143 143 81.5% 86.4% 86.4% HPLC Instrumentation: HPLC Test Report – 2000A Co-Polymer Coated CPG Solid Support with Unylinker(N-Ph) Item Value Item Value Data File 20260209-PS-1U-9    20260209_172607.dx Project Name Test Sequence Name

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